2012

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Bier C., Knauer S.K., Wünsch D., Kunst L., Scheiding S., Kaiser M., Ottmann C., Krämer, O.H., Stauber R.H.
Allosteric inhibition of Taspase1’s pathobiological activity by enforced dimerization in vivo.
The FASEB Journal 2012, 26(8):3421-9.

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Wünsch D., Fetz V., Heider D., Tenzer S., Bier C., Kunst L., Knauer S.K.,Stauber, R.H.
Chemico-genetic strategies to inhibit the leukemic potential of Threonin-Aspartase-1.
Blood Cancer Journal 2012, 2, e77; doi:10.1038/bcj.2012.22.

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Stauber R.H., Bier C., Knauer S.K.,
Letter - Targeting Taspase1 for cancer therapy.
Cancer Research 2012, 72(11):2912.

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Bier C., Hecht R., Kunst L., Scheiding S., Wünsch D., Goesswein D., Schneider, G., Krämer, O.H., Knauer S.K., Stauber R.H.
Overexpression of the catalytically impaired Taspase1T234V or Taspase1D233A variants does not have a dominant negative effect in t(4;11) leukemia cells.
PLOSone 2012, 7(5):e34142.

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Koutsimpelas D., Bjelopavlovic M., Yetis R., Frauenknecht K., Adryan B., Schmidtmann I., Gouveris H., Fruth K., Heinrich U.R., Stauber R.H., Mann W.J., Brieger J.
The VEGF/VEGF-R Axis in Sporadic Vestibular Schwannomas Correlates with Irradiation and Disease Recurrence.
ORL J Otorhinolaryngol Relat Spec. 2012, 74(6):330-8.

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Gebauer J.S., Malissek M., Simon S., Knauer S.K., Maskos M., Stauber R.H., Peukert W., Treuel L.
Impact of the nanoparticle-protein corona on colloidal stability and protein structure.
Langmuir 2012, 28(25):9673-9.

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Brandl A., Wagner T., Uhlig K.M., Knauer S.K., Stauber R.H., Melchior F., Schneider G., Heinzel T., Krämer O.H.
Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress.
Journal of Molecular Cell Biology 2012, 4(5):284-93.

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Labisso W.L., Wirth M., Stojanovic N., Stauber R.H., Schnieke A., Schmid R.M., Krämer O.H., Saur D., Schneider G.
MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors.
Cell Cycle 2012, 11(8):1593-602.

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Ginter T., Bier C., Knauer S.K., Sughra K., Hildebrand D., Münz T., Liebe T., Heller R., Henke A., Stauber R.H., Reichardt W., Schmid J.A., Kubatzky K.F., Heinzel T., Krämer O.H.
Histone deacetylase inhibitors block IFNγ-induced STAT1 phosphorylation.
Cellular Signaling 2012, 24(7):1453-60.

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Stauber R.H., Knauer S.K., Habtemichael N., Bier C., Unruhe B., Weisheit S., Spange S., Nonnenmacher F., Fetz V., Ginter T., Reichardt S., Liebmann C., Schneider G., Krämer O.H.
A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM- dependent apoptosis in head and neck cancer.
Oncotarget 2012, 3(1):31-43.